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Testim 1% Transdermal Testosterone Gel 5g/50mg (30 Tubes)

(20 customer reviews)

Original price was: $750.00.Current price is: $650.00.

Each 5g tube delivers 50mg testosterone (1% concentration) in a fast-drying gel base:

  • Active Ingredient: Testosterone USP (white crystalline powder; 17-β-hydroxyandrost-4-en-3-one).
  • Inactive Ingredients: Purified water, pentadecalactone, carbopol, acrylates, propylene glycol, glycerin, polyethylene glycol, ethanol (74%), tromethamine.

The formulation enhances absorption through shoulders/upper arms; avoid abdomen/genitals. Flammable due to high alcohol content—keep from heat/open flame.

Category:

Testim 1% Transdermal Testosterone Gel 5g/50mg (30 Tubes)

Testim 1% Transdermal Testosterone Gel (5g tube containing 50mg testosterone) from Endo Pharmaceuticals is a prescription topical androgen used for testosterone replacement therapy (TRT) in adult males with hypogonadism (low or absent endogenous testosterone). This clear, hydroalcoholic gel is applied daily to the skin for transdermal absorption, providing steady-state serum levels within 24 hours. The 30-tube carton (total 150g gel, 1.5g testosterone) supports a month’s supply at standard dosing. Originally developed by Auxilium Pharmaceuticals and now distributed by Endo USA, Inc., it’s a Schedule III controlled substance due to abuse potential. Not for women, children, or non-medical use—misuse risks serious health issues like cardiovascular events. Obtain via prescription with regular blood monitoring.

Composition

Each 5g tube delivers 50mg testosterone (1% concentration) in a fast-drying gel base:

  • Active Ingredient: Testosterone USP (white crystalline powder; 17-β-hydroxyandrost-4-en-3-one).
  • Inactive Ingredients: Purified water, pentadecalactone, carbopol, acrylates, propylene glycol, glycerin, polyethylene glycol, ethanol (74%), tromethamine.

The formulation enhances absorption through shoulders/upper arms; avoid abdomen/genitals. Flammable due to high alcohol content—keep from heat/open flame.

Potential Benefits (Based on Clinical Use and Patient Reports)

Indicated for primary/secondary hypogonadism (e.g., testicular failure, pituitary issues), it restores testosterone to normal range (300-1000 ng/dL), addressing:

  • Hormonal and Physical: Improves muscle mass, bone density (BMD increases incrementally over 12+ months), red blood cell production, and energy/fatigue.
  • Sexual Function: Enhances libido, erectile function, spontaneous erections (up to 137% increase at 30 days), and overall sexual motivation/desire.
  • Mood and Cognitive: Reduces depressive symptoms, boosts mood stability and vitality.
  • Long-Term Efficacy: 12-month studies show sustained benefits in body composition and sexual health without prostate symptom worsening.

Compared to patches, Testim yields 30-47% higher serum/free testosterone AUC; vs. AndroGel, faster absorption and higher peaks.

Usage and Dosage Guidelines

  • Typical Dosage: Start with 50mg (1 tube) once daily in the morning. Measure pre-dose serum testosterone ~14 days post-initiation; increase to 100mg (2 tubes) if below 300 ng/dL. Max 100mg/day.
  • Administration: Apply to clean, dry, intact skin of shoulders/upper arms (total ~450 cm² area). Rub in thoroughly; let dry (2-5 min). Wash hands with soap/water immediately after. Cover with clothing once dry; avoid showering/swimming for ≥2 hours. Do not apply to genitals/abdomen (higher transfer risk).
  • Duration: Long-term with periodic blood tests (testosterone, hematocrit, PSA every 3-6 months). Rotate sites; discard used tubes in trash (prevent access by others).
  • Special Instructions: For secondary exposure prevention, wash site before contact; pregnant women/children must avoid unwashed areas. Not interchangeable with other gels (e.g., AndroGel).

Consult endocrinologist for adjustments; confirm diagnosis with 2 AM testosterone readings <300 ng/dL.

Side Effects and Risks

Common (≥2% incidence, from 90-day trials):

  • Skin: Application site reactions (erythema, acne, pruritus; 16.1% overall).
  • Systemic: Increased hematocrit/hemoglobin (2.3-2.8%), emotional lability, headache, hypertension, mood swings.

Serious (post-marketing):

  • Secondary Exposure: Virilization in children/women (e.g., pubic hair, clitoromegaly, aggression); discontinue if occurs.
  • Cardiovascular: BP increases, VTE, edema (monitor in heart/renal patients).
  • Prostate/Breast: Worsened BPH, elevated PSA, gynecomastia, prostate cancer risk.
  • Hematologic: Polycythemia (hematocrit ≥54%; donate blood if needed).
  • Other: Sleep apnea exacerbation, liver injury (rare), priapism, infertility.

Contraindicated in prostate/breast cancer, pregnancy (fetal virilization), severe cardiac/hepatic/renal disease. Monitor lipids, liver enzymes; women/children: Avoid contact. Report to FDA at 1-800-FDA-1088.

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